Andrew Miri

Multi-area activity in mouse motor cortex associated with one- and two-handed oromanual dexterity

This study examines how motor cortex activity in mice changes during unimanual and bimanual food handling tasks, revealing distinct roles for different motor areas.

Interactions between motor cortical forelimb regions and their influence on muscles reorganize across behaviors

The paper shows that interactions between motor cortical regions change with behavior, with CFA dominating over RFA during climbing and vice versa during reaching.

Constraining inference of across-region interactions using neural activity perturbations

The paper shows that neural activity perturbations improve the accuracy of inferring across-region interactions in brain models.

A brain-wide, trial- and time-dependent deterministic drive synergizes with within-trial noise to time self-initiated actions

The paper shows that a deterministic drive across brain regions predicts action timing, which synergizes with trial-specific and within-trial noise to time self-initiated actions.

Hierarchy between forelimb premotor and primary motor cortices and its manifestation in their firing patterns

The paper investigates motor cortical hierarchy in mice by analyzing firing patterns during reaching, finding asymmetric influence but shared predictive activity between premotor and primary motor cortices.

Neural dynamics hierarchy in motor cortex and striatum across naturalistic behaviors

This study investigates neural dynamics in motor cortex and striatum across diverse motor behaviors in mice, finding a hierarchical organization that applies to both regions despite differences in behavior specificity and muscle activity correlation.

Distinct anatomical and functional corticospinal inputs innervate different spinal neuron types

The paper identifies distinct anatomical and functional corticospinal inputs to different spinal neuron types in mice, revealing homology to primate organization.

Selective direct motor cortical influence during naturalistic climbing in mice

The paper identifies selective direct motor cortical influence on limb muscles during climbing in mice, revealing distinct neural activity patterns.

Motor cortical influence relies on task-specific activity covariation

The paper shows that motor cortical activity covariation changes between tasks, driving distinct muscle activation patterns rather than relying on fixed flexion/extension programs or task-specific neuronal subsets.

Oculomotor plant and neural dynamics suggest gaze control requires integration on distributed timescales

This paper links oculomotor plant dynamics to neural integrator activity in larval zebrafish, showing that gaze stabilization requires integration across multiple distributed timescales.