Author

Xi Chen

Jiangsu Province HospitalORCID 0000-0002-5807-4219Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Xi Chen12 papers · AstraZeneca (United States)

Biology Disciplines

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Developmental Biology· 1 Genetics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Approach:statistical model· 1

Frequent Co-Authors

Anzhe Ma· 1 shared Bo WangiD· 1 shared Bo WangiD· 1 shared Donghui Chen· 1 shared Han Zhou· 1 shared Hongyu Chen· 1 shared Jianghua CheniD· 1 shared Jiuhuang Lan· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperImmunology

Anzhe Ma

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintSep 30, 2026

CD24-dependent innate immune checkpoint targeting chimera disrupts TGF-β-driven immunosuppression to enhance anti-tumor therapy

Ziyue Cui, Zhaoyi Lu, Mingzhu Pan…·Juan Zhang

This paper develops a bifunctional antibody-fusion protein that targets CD24 and TGF-β1 to disrupt immunosuppression and enhance anti-tumor therapy.

DOI 10.64898/2026.09.24.754107

humanexperimental assay

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Developmental BiologybioRxivPreprintMar 3, 2026

Exploration of the screening and regulatory mechanisms of biomarkers related to ac4C modification in laryngeal squamous cell carcinoma patients based on single-cell analysis and machine learning

Liqin Wang, Xiaoyang Gong, Donghui Chen…·Yawen Shi

The paper identifies seven ac4C-related prognostic genes in laryngeal squamous cell carcinoma using single-cell analysis and machine learning, showing their association with immune microenvironment alterations.

DOI 10.64898/2026.02.28.708684

humanbulk RNA-seq

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GeneticsbioRxivPreprintOct 25, 2022

Identification of plant-derived microRNAs in human kidney

Xi Chen, Xishao Xie, Lu Liu…·Longjiang Fan

The paper identifies plant-derived microRNAs in human kidney transplant patients and links three miRNAs to immune rejection.

DOI 10.1101/2022.10.25.513797

humanbulk RNA-seq

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