Author

Jane L. Armstrong

University of SunderlandORCID 0000-0002-5822-0597Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

Katie BestiD· 2 shared Laura WalkeriD· 2 shared Penny E. LovatiD· 2 shared Gian María FimiaiD· 1 shared Grant Richardson· 1 shared Ioana CosgareaiD· 1 shared John CasementiD· 1 shared Luca OcchigrossiiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBioinformatics

Katie BestORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

EndoMT: An R Package Resource for Endothelial-Mesenchymal Transition Gene Set Enrichment Analysis

Katie Best, John Casement, Penny E. Lovat, Laura Walker, Jane L. Armstrong

The paper introduces an R package for EndoMT gene set enrichment analysis, showing its utility in detecting EndoMT-associated transcriptional changes across different experimental conditions.

bioRxiv · Oct 5, 2026 · PreprintBioinformatics

Endothelial AMBRA1 loss contributes to vascular dysregulation facilitating metastatic progression in early-stage melanoma

Laura Walker, Roisin Stout, Martina Di Rienzo, Katie Best, Sofia Bisegna, Luca Occhigrossi, Ioana Cosgarea, Philip Sloan, Grant Richardson, Raffaele Strippoli, Mauro Piacentini, Gian María Fimia, Penny E. Lovat, Jane L. Armstrong

This study shows that endothelial AMBRA1 loss leads to vascular dysfunction and promotes metastasis in early-stage melanoma.

bioRxiv · Sep 30, 2026 · PreprintCancer Biology

Investigating the relationship Between AMBRA1 and Cell Proliferation in Melanoma

Milad Ibrahim, Marco Corazzari, Jane L. Armstrong, Noel M. Carter

This study examines AMBRA1's role in melanoma by analyzing transcriptomic changes from overexpression and knock-down, identifying novel cancer-related pathways and tumor suppressor functions.

bioRxiv · Jul 29, 2025 · PreprintCancer Biology