Author

Nengsong Luo

Chinese Academy of SciencesORCID 0000-0002-5822-6729Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:spatial transcriptomics· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Fuqiang XuiD· 4 shared Kunzhang LiniD· 4 shared Zengpeng HaniD· 3 shared Jie WangiD· 2 shared Yuxiang CaiiD· 2 shared Chaohui Ye· 1 shared Gangning Liu· 1 shared Jiaxin KouiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersNeuroscience

Fuqiang XuORCID

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4 papers

Recent·Most cited

AAV11 mediates efficient retrograde trans-neuronal transduction of astrocytes

Nengsong Luo, Yunling Gao, Zengpeng Han, Fuqiang Xu, Kunzhang Lin

This paper demonstrates that AAV11 enables retrograde trans-neuronal transduction of astrocytes, providing a tool to study astrocyte-neuron connectivity networks.

bioRxiv · Oct 10, 2025 · PreprintNeuroscience

Microglia-specific transduction via AAV11 armed with IBA1 promoter and miRNA-9 targeting sequences

Nengsong Luo, Kunzhang Lin, Yuxiang Cai, Xiaokai Sui, Zilian Zhang, Jiayong Xing, Gangning Liu, Wenjia Yuan, Jie Wang, Fuqiang Xu

This paper evaluates AAV11 vectors with IBA1 promoter and miRNA-9 sequences for microglia-specific transduction, finding AAV11 provides high specificity and efficiency in transducing microglia across brain regions and spinal cord.

bioRxiv · Jul 9, 2024 · PreprintNeuroscience

AAV11 permits efficient retrograde targeting of projection neurons

Zengpeng Han, Nengsong Luo, Wenyu Ma, Xiaodong Liu, Yuxiang Cai, Jiaxin Kou, Jie Wang, Lei Li, Siqi Peng, Zihong Xu, Wen Zhang, Yuxiang Qiu, Yang Wu, Chaohui Ye, Kunzhang Lin, Fuqiang Xu

The paper identifies rAAV11 as a highly efficient retrograde tracer for projection neurons, with improved transduction and utility for neural circuit monitoring and astrocyte targeting.

Nature Communications · Jun 26, 2023Peer-reviewedNeuroscience

Improved production and expanded application of CVS-N2c-ΔG virus for retrograde tracing

Kunzhang Lin, Lei Li, Wenyu Ma, Xin Yang, Zengpeng Han, Nengsong Luo, Fuqiang Xu

The paper improves the production of CVS-N2c-ΔG virus for retrograde tracing, showing higher efficiency and broader application in neural circuit studies.

bioRxiv · Jan 22, 2022 · PreprintNeuroscience