Alternate recognition by dengue protease: Proteolytic and binding assays provide functional evidence beyond an induced-fit
Mira A. M. Behnam, Christian D. P. Klein
The paper provides functional evidence that dengue protease recognizes substrates and inhibitors primarily through conformational selection rather than induced-fit, highlighting the impact of experimental conditions on ligand binding and proteolysis.
Biochimie · Jun 12, 2024Peer-reviewedBiochemistry