Pharmacology & ToxicologyJournal of Enzyme Inhibition and Medicinal ChemistryPeer-reviewed
Development of ketobenzothiazole-based peptidomimetic TMPRSS13 inhibitors with low nanomolar potency
Alexandre Joushomme, Antoine Désilets, William Champagne…·Richard Leduc
This study identifies low nanomolar TMPRSS13 inhibitors through chemical library screening and molecular modeling, showing their ability to block SARS-CoV-2 pseudovirus entry.