NeurosciencebioRxivPreprint
Reduced complexity of brain and behavior due to MeCP2 disruption and excessive inhibition
Jing Li, Patrick A. Kells, Shree Hari Gautam, Woodrow L. Shew
This study investigates how MeCP2 disruption in rats leads to excessive inhibition, increased neuronal synchrony, and stereotyped motor behavior, suggesting an E/I imbalance underlies motor dysfunction in Rett syndrome.
DOI 10.1101/2020.12.29.424632