Author

Sarah L. Castro-Wallace

Johnson Space CenterORCID 0000-0002-5852-6502Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:long-read sequencing· 2 Organism:bacteria (other)· 1 Approach:machine learning (classical)· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Aaron S. Burton· 2 shared Christopher E. MasoniD· 2 shared Kristen K. John· 2 shared Noah AlexanderiD· 2 shared Alexa B. R. McIntyreiD· 1 shared Alexa B.R. McIntyre· 1 shared Andrew Feinberg· 1 shared Angela M Yu· 1 shared

Activity by Year

2015-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersGenomics

Aaron S. Burton

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2 papers

Recent·Most cited

Nanopore detection of bacterial DNA base modifications

Alexa B. R. McIntyre, Noah Alexander, Aaron S. Burton, Sarah L. Castro-Wallace, Charles Y. Chiu, Kristen K. John, Sarah E. Stahl, Sheng Li, Christopher E. Mason

This study improves the detection of m6A in bacterial DNA using nanopore sequencing with a binary classifier, highlighting the importance of read quality and comparing results to PacBio methylation calls.

Nature Communications · Feb 4, 2019Peer-reviewedGenomics

Nanopore Sequencing in Microgravity

Alexa B.R. McIntyre, Lindsay Rizzardi, Angela M Yu, Gail L. Rosen, Noah Alexander, Douglas J. Botkin, Kristen K. John, Sarah L. Castro-Wallace, Aaron S. Burton, Andrew Feinberg, Christopher E. Mason

The paper tests nanopore sequencing in microgravity using a parabolic flight simulator and proposes new computational methods to address sequencing challenges in reduced gravity.

bioRxiv · Dec 10, 2015Genomics