Suppression of Fatty Acid Oxidation by Thioesterase Superfamily Member 2 in Skeletal Muscle Promotes Hepatic Steatosis and Insulin Resistance
Norihiro Imai, Hayley T. Nicholls, Michele Alves‐Bezerra, Yingxia Li, Anna Ivanova, Eric A. Ortlund, David E. Cohen
This study shows that deleting Them2 in skeletal muscle reduces weight gain and improves glucose homeostasis on a high-fat diet, but does not prevent hepatic steatosis.
Hepatology · Aug 25, 2021Peer-reviewedMolecular Biology