Author
University of California, San FranciscoORCID 0000-0002-5867-1531Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Timo Hagen, Isabelle Liu, Ariana A. Nagainis…·Hani Goodarzi
The paper introduces a synthetic gene atlas to study cis-regulatory elements across cell lines, enabling virtual-cell modeling by expanding gene regulatory networks with defined regulatory codes.
Brian J Woo, Sushil Sobti, Jung Min Suh…·Hani Goodarzi
The paper identifies RNF8 and MIS18A as chromatin organizers that modulate intratumoral heterogeneity in breast cancer, affecting therapeutic sensitivity and metastasis.
Heather M. Karner, Tabea Mittmann, Vicky Chen…·Hani Goodarzi
The paper identifies a metastasis-suppressive regulatory axis involving RBMS3 and TXNIP by analyzing mRNA stability in breast cancer using a deep-learning framework.
Matvei Khoroshkin, Arsenii O. Zinkevich, Elizaveta Aristova…·Hani Goodarzi
This paper introduces PARADE, a generative AI framework for designing mRNA UTRs with cell-type specificity, showing improved therapeutic efficacy in preclinical models.