Amir Momen-Roknabadi

The paper introduces a synthetic gene atlas to study cis-regulatory elements across cell lines, enabling virtual-cell modeling by expanding gene regulatory networks with defined regulatory codes.

Exai-1 is a transformer-based model that integrates RNA sequence and expression data to improve cfRNA analysis for disease detection.

The paper shows human cells adapt to methotrexate through stochastic tuning, a process similar to yeast, which is reversible and not mutation-driven.

The paper develops an inducible CRISPRi library for S. cerevisiae to systematically interrogate gene function with high precision and low false discovery rate.