NeurosciencebioRxivPreprint
ZNF91 is an endogenous repressor of the molecular phenotype associated with X-linked dystonia-parkinsonism (XDP)
Jimi L. Rosenkrantz, Sanaz Raghib, J. Elias Brandorff…·Frank M. J. Jacobs
This study shows that ZNF91 represses the XDP-SVA insertion and mitigates the molecular phenotype of XDP, with age-related ZNF91 expression decline contributing to disease progression.
DOI 10.1101/2023.10.20.563263