Jimi L. Rosenkrantz

This study shows that ZNF91 represses the XDP-SVA insertion and mitigates the molecular phenotype of XDP, with age-related ZNF91 expression decline contributing to disease progression.

This study examines ERVK11q23.3 expression in placental tissues, finding it upregulated in preterm placenta, expressed by trophoblasts, and involved in immune responses linked to preterm birth.

The paper compares transcriptomes of human and rhesus placenta, identifies differentially expressed genes, and develops novel rhesus trophoblast cell lines for studying placentation.

The paper uses single-cell DNA sequencing in non-human primates to show that chromosomal errors in embryos are encapsulated into micronuclei, fragmented, or excluded to prevent aneuploidy.

The paper identifies human-specific NOTCH2NL genes linked to neurodevelopmental disorders and shows they affect cortical neurogenesis through Notch signaling.