Comparison of DNA targeting CRISPR editors in human cells
Hongxin Huang, Weiqi Lv, Jinhe Li, Guanjie Huang, Zhihong Tan, Yongfei Hu, Shufeng Ma, Xin Zhang, Linxuan Huang, Ying Lin
This study compares DNA-targeting CRISPR editors in human cells, finding that Cas12f1 is suitable for activation, Cas12a for therapy, and Cas9 for in vitro and animal studies.
bioRxiv · Oct 20, 2022 · PreprintSynthetic Biology