Author

Jinhe Li

Third Affiliated Hospital of Southern Medical UniversityORCID 0009-0000-3633-7332Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Assay:CRISPR screen· 2 Approach:experimental assay· 2 Organism:human· 2

Frequent Co-Authors

Hongxin HuangiD· 2 shared Guanjie HuangiD· 1 shared Huaping ZhouiD· 1 shared Linxuan HuangiD· 1 shared Ming ZhouiD· 1 shared Qinchun LiangiD· 1 shared Shufeng MaiD· 1 shared Weiqi LviD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersSynthetic Biology

Hongxin HuangORCID

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2 papers

Recent·Most cited

Synthetic BiologyCellular & Molecular Biology LettersPeer-reviewedMay 17, 2023

Profiling the impact of the promoters on CRISPR-Cas12a system in human cells

Jinhe Li, Qinchun Liang, Huaping Zhou…·Hongxin Huang

The paper compares four promoters in the CRISPR-Cas12a system in human cells, finding CAG provides the highest editing efficiency while CMV and EF1a offer higher specificity.

10 citations

humanCRISPR screen

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Synthetic BiologybioRxivPreprintOct 20, 2022

Comparison of DNA targeting CRISPR editors in human cells

Hongxin Huang, Weiqi Lv, Jinhe Li…·Ying Lin

This study compares DNA-targeting CRISPR editors in human cells, finding that Cas12f1 is suitable for activation, Cas12a for therapy, and Cas9 for in vitro and animal studies.

DOI 10.1101/2022.10.20.513037

humanCRISPR screen

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