Author

Hongxin Huang

Guangzhou Medical University Cancer HospitalORCID 0000-0002-8656-4266Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Assay:CRISPR screen· 2 Approach:experimental assay· 2 Organism:human· 2

Frequent Co-Authors

Jinhe LiiD· 2 shared Guanjie HuangiD· 1 shared Huaping ZhouiD· 1 shared Linxuan HuangiD· 1 shared Ming ZhouiD· 1 shared Qinchun LiangiD· 1 shared Shufeng MaiD· 1 shared Weiqi LviD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersSynthetic Biology

Jinhe LiORCID

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2 papers

Recent·Most cited

Profiling the impact of the promoters on CRISPR-Cas12a system in human cells

Jinhe Li, Qinchun Liang, Huaping Zhou, Ming Zhou, Hongxin Huang

The paper compares four promoters in the CRISPR-Cas12a system in human cells, finding CAG provides the highest editing efficiency while CMV and EF1a offer higher specificity.

Cellular & Molecular Biology Letters · May 17, 2023Peer-reviewedSynthetic Biology

Comparison of DNA targeting CRISPR editors in human cells

Hongxin Huang, Weiqi Lv, Jinhe Li, Guanjie Huang, Zhihong Tan, Yongfei Hu, Shufeng Ma, Xin Zhang, Linxuan Huang, Ying Lin

This study compares DNA-targeting CRISPR editors in human cells, finding that Cas12f1 is suitable for activation, Cas12a for therapy, and Cas9 for in vitro and animal studies.

bioRxiv · Oct 20, 2022 · PreprintSynthetic Biology