Author
Washington University in St. LouisORCID 0000-0002-5873-351XUnclaimed ORCID profile · follow to get notified of new preprints
7 papers
Recent·Most cited
Mattia Medina Grespan, Muir J. Morrison, Brendan D. O’Fallon…·David P. Ng
EventHorizon is a foundation model for clinical flow cytometry that uses self-supervised learning to generate embeddings for diagnostic use, achieving high accuracy in identifying genetic abnormalities.
Kilannin Krysiak, Arpad M. Danos, Susanna Kiwala…·Malachi Griffith
The paper describes the evolution of the CIViC knowledgebase to meet the needs of the cancer variant interpretation community by expanding its functionality and data types.
Arpad M. Danos, Kilannin Krysiak, Erica Kay Barnell…·Obi L. Griffith
The paper describes the CIViC knowledge model and curation procedures for systematically organizing and interpreting cancer-related genetic variants.
Erica Kay Barnell, Adam Waalkes, Matthew Mosior…·Obi L. Griffith
The paper designs single molecule molecular inversion probes targeting clinically relevant variants using the CIViC database, demonstrating high sensitivity and discovering missed variants in cancer samples.
Erica Kay Barnell, Peter Ronning, Katie Marie Campbell…·Obi L. Griffith
This paper establishes a standard operating procedure for manual refinement of somatic variants in tumor sequencing data to improve consistency and reproducibility.
Obi L. Griffith, Nicholas C. Spies, Meenakshi Anurag…·Matthew J. Ellis
The paper identifies somatic mutations with prognostic effects in ER+ breast cancer using genomic data from multiple cohorts.
Kelsy C. Cotto, Alex Handler Wagner, Yang-Yang Feng…·Malachi Griffith
DGIdb 3.0 updates and expands the drug-gene interaction database by adding new sources, improving the codebase, and enhancing API features.