Author

Leonhard Wachutka

Technical University of MunichORCID 0000-0002-5959-040XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1 Research Focus:gene regulatory network inference· 1 Research Focus:software / tool· 1 Organism:yeast· 1

Frequent Co-Authors

Julien GagneuriD· 3 shared Patrick CrameriD· 2 shared Agnieszka NadeliD· 1 shared Arcangela IusoiD· 1 shared Björn SchwalbiD· 1 shared Carina Demel· 1 shared Eliška KoňaříkováiD· 1 shared Gabriel VillamiliD· 1 shared

Activity by Year

2016-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersMolecular Biology

Julien GagneurORCID

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3 papers

Recent·Most cited

Transient transcriptome sequencing: computational pipeline to quantify genome-wide RNA kinetic parameters and transcriptional enhancer activity

Gabriel Villamil, Leonhard Wachutka, Patrick Cramer, Julien Gagneur, Björn Schwalb

This paper presents a computational pipeline for analyzing TT-seq data to quantify RNA kinetic parameters and enhancer activity.

bioRxiv · Jun 4, 2019 · PreprintMolecular Biology

OCR-Stats: Robust estimation and statistical testing of mitochondrial respiration activities using Seahorse XF Analyzer

Vicente A. Yépez, Laura Sophie Kremer, Arcangela Iuso, Mirjana Gušić, Robert Kopajtich, Eliška Koňaříková, Agnieszka Nadel, Leonhard Wachutka, Holger Prokisch, Julien Gagneur

This study develops OCR-Stats, a statistical method to improve the accuracy of mitochondrial respiration measurements from Seahorse XF Analyzer data by addressing noise and variation across plates and wells.

PLoS ONE · Jul 11, 2018Peer-reviewedBioinformatics

Determinants of RNA metabolism in the Schizosaccharomyces pombe genome

Philipp Eser, Leonhard Wachutka, Kerstin C Maier, Carina Demel, Mariana Boroni, Srignanakshi Iyer, Patrick Cramer, Julien Gagneur

The paper defines sequence elements that regulate RNA metabolism in S. pombe by improving genome annotation and combining RNA labeling with mathematical modeling.

Molecular Systems Biology · Feb 16, 2016Peer-reviewedGenomics