Conserved T cell receptor usage underpins recognition of CD1c presenting a mycobacterial lipid
Thinh-Phat Cao, Caroline Soliman, Samuel J. Redmond…·Nicholas A. Gherardin
The paper identifies a conserved TCR motif recognizing mycobacterial lipids presented by CD1c, showing higher frequencies in TB-endemic regions and providing a cryo-EM structure of the interaction.