Developmental BiologybioRxivPreprint
Evolution of abbreviated development in Heliocidaris erythrogramma dramatically re-wired the highly conserved sea urchin developmental gene regulatory network to decouple signaling center function from ultimate fate
Allison Edgar, Maria Byrne, David R. McClay, Gregory A. Wray
This paper constructs the first formal GRN for Heliocidaris erythrogramma, showing its developmental GRN differs significantly from ancestral sea urchins, suggesting selection over constraint in GRN conservation.