Gregory A. Wray

HiFi-Helper provides a workflow for genome assembly using HiFi reads, achieving quality comparable to older methods with less time and resources.

The paper identifies ivory:mir-193 as a master regulator of scale type differentiation in Heliconius butterflies, showing it converts Type II scales to Type I and influences Type III scale development through readthrough transcription.

This study uses single-nucleus transcriptomics to investigate sex-specific gene expression in wing scale cells of Colias eurytheme butterflies, revealing regulatory mechanisms underlying sexual dimorphism.

The paper shows human-specific variants in HARE5 enhance enhancer activity, promoting progenitor proliferation and contributing to human cortical expansion.

This study shows that lepidopteran scale cells originate from sensory organ precursors through a canonical lineage, supported by live imaging and single-nucleus RNA sequencing.

The paper uses single-cell RNA sequencing to compare embryonic development in two sea urchin species, identifying evolutionary changes in cell fate specification and signaling.

The paper analyzes single-cell RNA-seq data from sea urchin development to compare larval and adult body plan formation, identifying regulatory gene differences and cell type changes.

This paper demonstrates the use of DsiRNA for functional studies in sea urchin embryos, showing its effectiveness in knocking down genes and analyzing Nodal signaling gradients.

The paper uses scRNA-seq and computational methods to study developmental trajectories and gene regulatory networks in sea urchin embryos, revealing lineage diversification and timing differences between species.

This paper constructs the first formal GRN for Heliocidaris erythrogramma, showing its developmental GRN differs significantly from ancestral sea urchins, suggesting selection over constraint in GRN conservation.

The paper evaluates chromatin accessibility in prefrontal cortex samples from schizophrenia cases and controls, finding high heritability enrichment in open chromatin regions but no differential accessibility between groups.