BiochemistryJournal of Structural BiologyPeer-reviewed
Structural divergence in N-terminal domains of AAA proteases paraplegin (SPG7) and FtsH indicates a key structural function in complex formation
James G. Hyatt, Neil G. Paterson, Juliette M. Devos…·Anja Winter
This study compares the structural properties of the N-terminal domains of human paraplegin (SPG7) and bacterial FtsH, revealing differences in oligomerization and domain-swapping that may contribute to AAA protease function and disease.
DOI 10.1016/j.jsb.2026.108353