Neil G. Paterson

Structural divergence in N-terminal domains of AAA proteases paraplegin (SPG7) and FtsH indicates a key structural function in complex formation

This study compares the structural properties of the N-terminal domains of human paraplegin (SPG7) and bacterial FtsH, revealing differences in oligomerization and domain-swapping that may contribute to AAA protease function and disease.

Constructing synthetic-protein assemblies from de novo designed 310 helices

This paper designs and characterizes synthetic protein assemblies composed of 310 helices, demonstrating their ability to form stable structures despite their rarity in natural proteins.