Author

Ariane Beauvais

Ottawa Hospital Research InstituteORCID 0000-0002-6029-7470Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Aoife ReillyiD· 2 shared Rashmi KotharyiD· 2 shared Rebecca YaworskiiD· 2 shared Benjamin P. KleinstiveriD· 1 shared Bernard Laurent SchneideriD· 1 shared Casey A. MaguireiD· 1 shared Christiano R. R. AlvesiD· 1 shared Cícera Regina LazzarottoiD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersGenetics

Aoife ReillyORCID

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2 papers

Recent·Most cited

GeneticsbioRxivPreprintJan 20, 2023

Base editing as a genetic treatment for spinal muscular atrophy

Christiano R. R. Alves, Leillani L. Ha, Rebecca Yaworski…·Benjamin P. Kleinstiver

This paper describes the optimization of base editing to correct the SMN2 exon 7 mutation in SMA, achieving high editing efficiency and increased SMN protein levels in vitro and in vivo.

20 citations

mouseexperimental assay

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Molecular BiologybioRxivPreprintNov 8, 2021

Central and peripheral delivery of AAV9-SMN target different pathomechanisms in a mouse model of spinal muscular atrophy

Aoife Reilly, Marc‐Olivier Deguise, Ariane Beauvais…·Rashmi Kothary

The paper compares IV and ICV delivery of AAV9-SMN in SMA mice, showing different SMN restoration patterns and treatment outcomes.

1 citation

mouseexperimental assay

𝕏 PostBluesky