Author

Mingrui Zhang

Hebei Medical UniversityORCID 0000-0002-6033-1595Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Research Focus:gene regulatory network inference· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:differential expression· 1

Frequent Co-Authors

Chongyang YuaniD· 2 shared Xiaoyan WangiD· 2 shared Yaqi Chi· 2 shared Yuxing CheniD· 2 shared Li YangiD· 1 shared Liuchang Yang· 1 shared Ming Li· 1 shared Ming LiiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersMicrobiology

Chongyang YuanORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintAug 5, 2026

Defining the genetic landscape of acid and oxidative stress tolerance in Streptococcus mutans by pooled CRISPR interference screening

Yaqi Chi, Yuxing Chen, Chongyang Yuan…·Yongliang Li

This study identifies genes critical for acid and oxidative stress tolerance in Streptococcus mutans using CRISPRi screens and reveals core physiological processes involved in stress adaptation.

DOI 10.64898/2026.08.04.742890

bacteria (other)genetic perturbation / CRISPR

MicrobiologybioRxivPreprintJul 22, 2025

Construction of a genome-wide pooled CRISPRi library as a resource for exploring the acid tolerance mechanism in Streptococcus mutans

Yaqi Chi, Chen Yuxing, Chongyang Yuan…·Yongliang Li

The paper constructs a genome-wide CRISPRi library to identify acid tolerance genes in S. mutans and finds 95 associated genes involved in metabolism, tRNA modification, and transcriptional regulation.

DOI 10.1101/2025.07.22.666072

bacteria (other)genetic perturbation / CRISPR