Author

Yaqi Chi

Peking University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 3 Research Focus:gene regulatory network inference· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:protein structure· 1

Frequent Co-Authors

Xiaoyan WangiD· 3 shared Yuxing CheniD· 3 shared Chongyang YuaniD· 2 shared Liuchang Yang· 2 shared Mingrui ZhangiD· 2 shared Yongliang LiiD· 2 shared Fengjiao XiniD· 1 shared Jiahao NiuiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersMicrobiology

Xiaoyan WangORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Defining the genetic landscape of acid and oxidative stress tolerance in Streptococcus mutans by pooled CRISPR interference screening

Yaqi Chi, Yuxing Chen, Chongyang Yuan, Li Yang, Mingrui Zhang, Xiaolin Chen, Yiran Zhao, Ming Li, Xiaoyan Wang, Yongliang Li

This study identifies genes critical for acid and oxidative stress tolerance in Streptococcus mutans using CRISPRi screens and reveals core physiological processes involved in stress adaptation.

bioRxiv · Aug 5, 2026 · PreprintMicrobiology

Construction of a genome-wide pooled CRISPRi library as a resource for exploring the acid tolerance mechanism in Streptococcus mutans

Yaqi Chi, Chen Yuxing, Chongyang Yuan, Liuchang Yang, Mingrui Zhang, Xiaolin Chen, Yiran Zhao, Ming Li, Xiaoyan Wang, Yongliang Li

The paper constructs a genome-wide CRISPRi library to identify acid tolerance genes in S. mutans and finds 95 associated genes involved in metabolism, tRNA modification, and transcriptional regulation.

bioRxiv · Jul 22, 2025 · PreprintMicrobiology

Particular Amino Acid on Lateral Interface Maintains FtsZ Function Under Acid Stress in Streptococcus mutans

Yuxing Chen, Yongliang Li, Jiahao Niu, Liuchang Yang, Yaqi Chi, Xue Cai, Fengjiao Xin, Jie Zhang, Xianyang Fang, Manas Mondal, Yiqin Gao, Xiaoyan Wang

This study identifies Arg68 on the lateral interface of S. mutans FtsZ as critical for maintaining its function under acid stress, offering a potential target for antimicrobial drugs.

bioRxiv · Jan 26, 2025 · PreprintMicrobiology