Author

Pier Paolo Scaglioni

University of CincinnatiORCID 0000-0002-6036-5138Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Agnese Marucci· 1 shared Ahmad T. MansouriD· 1 shared Caterina BartolacciiD· 1 shared Cristina AndreaniiD· 1 shared Gina M. DeNicolaiD· 1 shared Jessica A. KilgoreiD· 1 shared Lorenzo LucianiiD· 1 shared Margherita MelegariiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Agnese Marucci

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintJul 25, 2025

Thioredoxin Reductase 1 inhibition triggers ferroptosis in KRAS-independent lung cancers

Cristina Andreani, Caterina Bartolacci, Margherita Melegari…·Pier Paolo Scaglioni

The paper identifies TXNRD1 as a therapeutic target in KRAS-WT and KRASi-resistant lung cancers by showing TRXR1 inhibition induces ferroptosis through redox mechanisms.

3 citations

humanbulk RNA-seq

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