Author

Christl Gaubitz

University of CopenhagenORCID 0000-0002-6047-9282Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1

Frequent Co-Authors

Alejandro Garcia Lopez· 1 shared Alessandra ZarantonelloiD· 1 shared Alexander A.L. JorgeiD· 1 shared Andreas Ingham· 1 shared Antonio Amorin· 1 shared Antônio Marcondes LerárioiD· 1 shared Brendan PageiD· 1 shared Brian A. KelchiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Alejandro Garcia Lopez

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2 papers

Recent·Most cited

ZATT/ZNF451 promotes release of stalled TOP2 cleavage complexes

Xueyuan Leng, Alessandra Zarantonello, Sampath Amitash Gadi, Ellen S. Kakulidis, Pierre Fey, Andreas Ingham, Ivo Alexander Hendriks, Sidak Minocha, Camilla S. Colding-Christensen, Stella Munkholm Kristensen, Simon Willaume, Natalie Palkova, Christl Gaubitz, Alejandro Garcia Lopez, Poul Martin Bendix, , Julien P. Duxin

This study identifies ZATT/ZNF451 as a key factor in resolving stalled TOP2 cleavage complexes without relying on TDP2, proteolysis, or DSB repair pathways.

bioRxiv · Jul 15, 2026 · PreprintMolecular Biology

PCNA thermosensitivity underlies an Ataxia Telangiectasia-like disorder

Joe Magrino, Veridiana Munford, Davi Jardim Martins, Thaís Kataoka Homma, Brendan Page, Christl Gaubitz, Bruna Lucheze Freire, Antônio Marcondes Lerário, Juliana Brandstetter Vilar, Antonio Amorin, Emília Katiane Embiruçu de Araújo Leão, Fernando Kok, Carlos Frederico Martins Menck, Alexander A.L. Jorge, Brian A. Kelch

The paper identifies a second PCNA mutation, C148S, causing PARD, showing both variants have thermo-stability defects leading to reduced chromatin-bound PCNA and temperature-dependent phenotypes.

medRxiv · Oct 20, 2022 · PreprintGenetic & Genomic Medicine