Author

Christopher M. R. Lang

University of BaselORCID 0000-0002-6052-6835Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 1

Frequent Co-Authors

Christian MittelholzeriD· 2 shared David HauseriD· 2 shared Enja Tatjana KipferiD· 2 shared Fabian OtteiD· 2 shared Lorena UrdaiD· 2 shared Martin Joseph LettiD· 2 shared Thomas KlimkaitiD· 2 shared Yuepeng ZhangiD· 2 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Christian MittelholzerORCID

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2 papers

Recent·Most cited

Rapid cloning-free mutagenesis of new SARS-CoV-2 variants using a novel reverse genetics platform

Enja Tatjana Kipfer, David Hauser, Martin Joseph Lett, Fabian Otte, Lorena Urda, Yuepeng Zhang, Christopher M. R. Lang, Mohamed Chami, Christian Mittelholzer, Thomas Klimkait

The paper introduces a cloning-free reverse genetics platform for rapidly engineering SARS-CoV-2 variants and applies it to rescue Chikungunya and Dengue viruses.

eLife · Aug 11, 2023Peer-reviewedMolecular Biology

Single-cycle SARS-CoV-2 vaccine elicits high protection and sterilizing immunity in hamsters

Martin Joseph Lett, Fabian Otte, David Hauser, Jacob Schön, Enja Tatjana Kipfer, Donata Hoffmann, Nico Joël Halwe, Lorenz Ulrich, Yuepeng Zhang, Vladimir Cmiljanović, Claudia Wylezich, Lorena Urda, Christopher M. R. Lang, Martin Beer, Christian Mittelholzer, Thomas Klimkait

This study develops a single-cycle SARS-CoV-2 vaccine that provides full protection and sterilizing immunity in hamsters against autologous challenge.

bioRxiv · May 17, 2023 · PreprintMolecular Biology