Author
Thomas Klimkait
University of BaselORCID 0000-0003-4945-6511Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2021-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 21 mutual co-author links5 papers
Recent·Most cited
- Molecular BiologyeLifePeer-reviewed
Rapid cloning-free mutagenesis of new SARS-CoV-2 variants using a novel reverse genetics platform
Enja Tatjana Kipfer, David Hauser, Martin Joseph Lett…·Thomas Klimkait
The paper introduces a cloning-free reverse genetics platform for rapidly engineering SARS-CoV-2 variants and applies it to rescue Chikungunya and Dengue viruses.
14 citations - Molecular BiologybioRxivPreprint
Single-cycle SARS-CoV-2 vaccine elicits high protection and sterilizing immunity in hamsters
Martin Joseph Lett, Fabian Otte, David Hauser…·Thomas Klimkait
This study develops a single-cycle SARS-CoV-2 vaccine that provides full protection and sterilizing immunity in hamsters against autologous challenge.
DOI 10.1101/2023.05.17.541127 - Genetic & Genomic MedicineMolecular Biology and EvolutionPeer-reviewed
A phylogeny-aware GWAS framework to correct for heritable pathogen effects on infectious disease traits
Sarah Nadeau, Christian Wandall Thorball, Roger D. Kouyos…·S Yerly
This paper introduces a phylogeny-aware GWAS framework to correct for heritable pathogen effects on infectious disease traits, showing improved detection of host genetic variants in simulations and applied to HIV-1 data.
DOI 10.1093/molbev/msac163 - Genetic & Genomic MedicineScientific ReportsPeer-reviewed
The influence of human genetic variation on Epstein-Barr virus sequence diversity
Sina Rüeger, Christian Hammer, Alexis Loetscher…·Sabine Yerly
The paper investigates how human genetic variation influences Epstein-Barr virus (EBV) sequence diversity by analyzing paired viral and human genomic data from HIV-coinfected individuals.
15 citations