Escalating High-dimensional Imaging using Combinatorial Channel Multiplexing and Deep Learning
Raz Ben-Uri, Lior Ben Shabat, Dana Shainshein, Omer Bar-Tal, Yuval Bussi, Noa Maimon, Tal Keidar Haran, Idan Milo, Inna Goliand, Yoseph Addadi, Tomer‐Meir Salame, Alexander Rochwarger, Christian M. Schürch, Shai Bagon, Ofer Elhanani, Leeat Keren
This paper introduces CombPlex, a combinatorial staining method combined with deep learning to measure more proteins at single-cell resolution without needing specialized imaging equipment.
bioRxiv · Sep 9, 2023 · PreprintSystems Biology