Author

Arun Gonzales Decano

Dublin City UniversityORCID 0000-0002-6058-6483Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:E. coli· 5 Approach:statistical model· 4 Assay:whole-genome sequencing· 4 Approach:experimental assay· 2 Research Focus:phylogenetics / evolution· 2 Research Focus:gene regulatory network inference· 1 Assay:protein sequence· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Tim DowningiD· 5 shared Alexander D. RahmiD· 2 shared Catherine LuddeniD· 2 shared Julian ParkhilliD· 2 shared Nghia T. H. TraniD· 2 shared Buthaina Al-AwadiiD· 1 shared Caitriona WoodsiD· 1 shared Cian SmythiD· 1 shared

Activity by Year

2019-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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5 shared papersGenomics

Tim DowningORCID

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Author profile →

5 papers

Recent·Most cited

Plasmids shape the diverse accessory resistomes of Escherichia coli ST131

Arun Gonzales Decano, Nghia T. H. Tran, Hawriya Al-Foori, Buthaina Al-Awadi, Leigh Campbell, Kevin Ellison, Louisse Paola Mirabueno, Maddy Nelson, Shane Power, J. Smith, Cian Smyth, Zoe Vance, Caitriona Woods, Alexander D. Rahm, Tim Downing

The paper examines the AMR gene diversity in ST131 E. coli using a preterm infant resistome, showing that plasmids drive AMR gene composition through conjugation and recombination.

Access Microbiology · Nov 18, 2020Peer-reviewedGenomics

Genomic surveillance of Escherichia coli ST131 identifies local expansion and serial replacement of subclones

Catherine Ludden, Arun Gonzales Decano, Dorota M. Jamrozy, Derek Pickard, Dearbháile Morris, Julian Parkhill, Sharon J. Peacock, Martin Cormican, Tim Downing

The paper analyzes global E. coli ST131 genomes to trace the evolution and spread of antibiotic-resistant subclones, identifying a C2 lineage that displaced a C1 strain in an Irish LTCF.

Microbial Genomics · Mar 26, 2020Peer-reviewedGenomics

An Escherichia coli ST131 pangenome atlas reveals population structure and evolution across 4,071 isolates

Arun Gonzales Decano, Tim Downing

The paper uses population genomics to analyze 4,071 E. coli ST131 isolates, revealing population structure, evolutionary relationships, and dynamics of AMR genes across three main clades and their subclades.

Scientific Reports · Nov 22, 2019Peer-reviewedGenomics

Complete assembly of Escherichia coli ST131 genomes using long reads demonstrates antibiotic resistance gene variation within diverse plasmid and chromosomal contexts

Arun Gonzales Decano, Catherine Ludden, Theresa Feltwell, Kim Judge, Julian Parkhill, Tim Downing

This study uses long-read sequencing to assemble E. coli ST131 genomes, revealing diverse plasmid and chromosomal contexts of antibiotic resistance genes.

mSphere · May 7, 2019Peer-reviewedGenomics

Protein-protein interaction network topology as a measure of bacterial plasmid-chromosome co-evolution

Nghia T. H. Tran, Arun Gonzales Decano, Tim Downing, Alexander D. Rahm

The paper examines plasmid-chromosome gene interactions in E. coli to identify a new invariant of bacterial protein-protein interaction networks related to co-evolution.

bioRxiv · Apr 16, 2019 · PreprintBioinformatics