Author

Catherine Ludden

Wellcome Sanger InstituteORCID 0000-0001-9503-0744Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:E. coli· 3 Assay:whole-genome sequencing· 3 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Research Focus:phylogenetics / evolution· 1

Frequent Co-Authors

Julian ParkhilliD· 3 shared Arun Gonzales DecanoiD· 2 shared Dorota M. JamrozyiD· 2 shared Sharon J. PeacockiD· 2 shared Tim DowningiD· 2 shared Beth BlaneiD· 1 shared Carolyne HorneriD· 1 shared Dearbháile MorrisiD· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersGenomics

Julian ParkhillORCID

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3 papers

Recent·Most cited

Genomic surveillance of Escherichia coli ST131 identifies local expansion and serial replacement of subclones

Catherine Ludden, Arun Gonzales Decano, Dorota M. Jamrozy, Derek Pickard, Dearbháile Morris, Julian Parkhill, Sharon J. Peacock, Martin Cormican, Tim Downing

The paper analyzes global E. coli ST131 genomes to trace the evolution and spread of antibiotic-resistant subclones, identifying a C2 lineage that displaced a C1 strain in an Irish LTCF.

Microbial Genomics · Mar 26, 2020Peer-reviewedGenomics

Complete assembly of Escherichia coli ST131 genomes using long reads demonstrates antibiotic resistance gene variation within diverse plasmid and chromosomal contexts

Arun Gonzales Decano, Catherine Ludden, Theresa Feltwell, Kim Judge, Julian Parkhill, Tim Downing

This study uses long-read sequencing to assemble E. coli ST131 genomes, revealing diverse plasmid and chromosomal contexts of antibiotic resistance genes.

mSphere · May 7, 2019Peer-reviewedGenomics

One Health genomic surveillance of Escherichia coli demonstrates distinct lineages and mobile genetic elements in isolates from humans versus livestock

Catherine Ludden, Kathy E. Raven, Dorota M. Jamrozy, Theodore Gouliouris, Beth Blane, Francesc Coll, Marcus Christofoor de Goffau, Plamena Naydenova, Carolyne Horner, Juan Hernandez-Garcia, Paul M. Wood, Nazreen F. Hadjirin, Milorad Radakovic, Nicholas M. Brown, Mark Holmes, , Sharon J. Peacock

The paper compares E. coli isolates from humans and livestock to assess transmission and resistance gene sharing, finding genetic distinctions and limited shared antimicrobial resistance genes.

mBio · Jan 21, 2019Peer-reviewedGenomics