Author

David Creytens

Ghent University HospitalORCID 0000-0002-6064-1673Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:genetic perturbation / CRISPR· 1 Organism:Xenopus· 1

Frequent Co-Authors

Arne ChristiaensiD· 1 shared Dieter TulkensiD· 1 shared Kris VleminckxiD· 1 shared Marthe BoelensiD· 1 shared Suzan DemuynckiD· 1 shared Wout HoubartiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperCancer Biology

Arne ChristiaensORCID

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1 paper

Recent·Most cited

A CRISPR-based Xenopus tropicalis model for retroperitoneal liposarcoma with genetic control over the dedifferentiation process

Marthe Boelens, Dieter Tulkens, Arne Christiaens, Wout Houbart, Suzan Demuynck, David Creytens, Kris Vleminckx

This paper establishes a Xenopus tropicalis model of liposarcoma by perturbing p53 and Rb pathways, showing that pathway deregulation initiates tumors and that ep300 disruption promotes dedifferentiation.

bioRxiv · Mar 30, 2026 · PreprintCancer Biology