Author

Jayne Aiken

University of Colorado AnschutzORCID 0000-0002-6084-602XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Benjamin L. ProsseriD· 1 shared Carris Temera BorlandiD· 1 shared Emily Anne BatesiD· 1 shared Emily Anne BatesiD· 1 shared Erika L.F. HolzbauriD· 1 shared Georgia BuscagliaiD· 1 shared Jeffrey K. MooreiD· 1 shared Katelyn J. HoffiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperNeuroscience

Benjamin L. ProsserORCID

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3 papers

Recent·Most cited

Pathogenic KIF1A variants differentially disrupt axonal trafficking and impede synaptic development

Jayne Aiken, Carris Temera Borland, Nicolas Marotta, Benjamin L. Prosser, Erika L.F. Holzbaur

This study investigates how pathogenic KIF1A variants affect axonal trafficking and synaptic development in human neurons using gene-edited iPSCs.

The Journal of Cell Biology · Aug 12, 2026Peer-reviewedNeuroscience

Tuba1a is uniquely important for axon guidance through midline commissural structures

Georgia Buscaglia, Jayne Aiken, Katelyn J. Hoff, Kyle R. Northington, Emily Anne Bates

The paper shows that reduced Tuba1a impairs axon guidance but supports neuronal migration, revealing TUBA1A's role in microtubule dynamics during neurodevelopment.

bioRxiv · May 5, 2020 · PreprintDevelopmental Biology

TUBA1A mutations identified in lissencephaly patients dominantly disrupt neuronal migration and impair dynein activity

Jayne Aiken, Jeffrey K. Moore, Emily Anne Bates

Human Molecular Genetics · Nov 29, 2018Peer-reviewedDevelopmental Biology