Author

Carris Temera Borland

University of PennsylvaniaORCID 0000-0002-7550-2692Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

Erika L.F. HolzbauriD· 2 shared Benjamin L. ProsseriD· 1 shared Jacob PopolowiD· 1 shared Jayne AikeniD· 1 shared Nicolas MarottaiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 7 mutual co-author links

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2 shared papersNeuroscience

Erika L.F. HolzbaurORCID

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2 papers

Recent·Most cited

NeuroscienceThe Journal of Cell BiologyPeer-reviewedAug 12, 2026

Pathogenic KIF1A variants differentially disrupt axonal trafficking and impede synaptic development

Jayne Aiken, Carris Temera Borland, Nicolas Marotta…·Erika L.F. Holzbaur

This study investigates how pathogenic KIF1A variants affect axonal trafficking and synaptic development in human neurons using gene-edited iPSCs.

2 citationstop 5%

humanexperimental assay

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NeurosciencebioRxivPreprintJul 24, 2026

KIF1A-mediated trafficking is required for neuronal autophagy in human neurons

Carris Temera Borland, Jacob Popolow, Erika L.F. Holzbaur

This study shows that KIF1A mutations impair autophagy in human neurons by disrupting ATG9 trafficking and lysosomal function, contributing to KAND pathogenesis.

DOI 10.64898/2026.07.22.740140

humanexperimental assay

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