Clustered VEGF Nanoparticles in Microporous Annealed Particle (MAP) Hydrogel Accelerates Functional Recovery and Brain Tissue Repair after Stroke
Kevin Erning, Katrina L. Wilson, Cara S. Smith, Long Nguyen, Neica I. Joseph, Rachel Irengo, Lauren Y. Cao, Mohanapriya Cumaran, Yi Shi, Sihan Lyu, Lindsay Riley, Timothy Dunn, Stanley Thomas Carmichael, Tatiana Segura
This study develops VEGF-coated heparin nanoparticles in MAP hydrogels to promote brain repair after stroke, showing improved tissue formation and functional recovery without free heparin.
bioRxiv · Jan 30, 2025 · PreprintBioengineering