Author

Rune Kleppe

Haukeland University HospitalORCID 0000-0002-6086-755XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

Jan HaavikiD· 2 shared Anne Baumann· 1 shared Christian TotlandiD· 1 shared Elaheh MahootchiiD· 1 shared Even BirkelandiD· 1 shared Floriana MogaveroiD· 1 shared Hrvoje MiletićiD· 1 shared Ingeborg WingeiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMolecular Biology

Jan HaavikORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintSep 5, 2023

The effects of phenylalanine and tyrosine levels on dopamine production in rat PC12 cells. Implications for treatment of phenylketonuria and tyrosinemia type 1

Peter D. Szigetvari, Sudarshan S. Patil, Even Birkeland…·Jan Haavik

The paper investigates how phenylalanine and tyrosine levels affect dopamine production in PC12 cells, revealing molecular mechanisms linking these amino acids to dopamine synthesis in PKU and TYRSN1.

DOI 10.1101/2023.09.05.556372

ratproteomics

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NeuroscienceScience AdvancesPeer-reviewedJul 17, 2020

GADL1 is a multifunctional decarboxylase with tissue specific roles in β-alanine and carnosine production

Elaheh Mahootchi, Selina Cannon Homaei, Rune Kleppe…·Jan Haavik

This study identifies GADL1 as a multifunctional enzyme involved in β-alanine and carnosine production, showing its tissue-specific roles and associations with physiological traits in mice and humans.

47 citations

mouseexperimental assay

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