GenomicsLeukemiaPeer-reviewed
Contribution of CTCF binding to transcriptional activity at the HOXA locus in NPM1-mutant AML cells
Reza Ghasemi, Heidi Struthers, Elisabeth R. Wilson, David H. Spencer
The paper investigates the role of CTCF binding in regulating HOXA gene expression in NPM1-mutant AML cells and finds that transcriptional activity does not require long-range CTCF-mediated chromatin interactions.