Author

Luis Fernando Barrera

Universidad de AntioquiaORCID 0000-0002-6108-6747Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Andrés BaenaiD· 2 shared Ana Esteve‐SoléiD· 1 shared Andrés Augusto AriasiD· 1 shared Aniss RafikiD· 1 shared Anne PueliD· 1 shared Antoni Noguera‐JuliániD· 1 shared Aurélie CobatiD· 1 shared Ayça Aslan KıykımiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetics

Andrés BaenaORCID

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2 papers

Recent·Most cited

GeneticsThe Journal of Experimental MedicinePeer-reviewedJul 9, 2026

✦ In-depth digest

Humans homozygous for rare or common hypomorphic IL23R variants are prone to tuberculosis

Diana Olguín-Calderón, Laura E. Kilpatrick, Clément Conil…·Stéphanie Boisson‐Dupuis

Homozygosity for hypomorphic IL23R variants (G149R, G300V, R381Q) partly impairs IL-23-dependent IFN-γ production in patient cells; with L372F (effect inferred), they are enriched in tuberculosis, not MSMD or CMC patients.

1 citation

humanwhole-exome sequencing

𝕏 PostBluesky

Systems BiologyPLoS Computational BiologyPeer-reviewedJun 15, 2020

A systematic evaluation of Mycobacterium tuberculosis Genome-Scale Metabolic Networks

Víctor A. López-Agudelo, Tom A. Mendum, Emma Laing…·Rigoberto Ríos‐Estepa

This study evaluates eight Mtb metabolic models to identify the best performing ones and refine them for future research.

29 citations

whole-genome sequencingstatistical model

𝕏 PostBluesky