Author

Laura E. Kilpatrick

University of NottinghamORCID 0000-0001-6331-5606Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Assay:proteomics· 1

Frequent Co-Authors

Simon PlattiD· 2 shared Stephen John HilliD· 2 shared Alessandro GennaiD· 1 shared Ana Esteve‐SoléiD· 1 shared Andrés Augusto AriasiD· 1 shared Andrés BaenaiD· 1 shared Aniss RafikiD· 1 shared Anne PueliD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersGenetics

Simon PlattORCID

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2 papers

Recent·Most cited

Humans homozygous for rare or common hypomorphic IL23R variants are prone to tuberculosis

Diana Olguín-Calderón, Laura E. Kilpatrick, Clément Conil, Quentin Philippot, Masato Ogishi, Joseph Vellutini, Ji Eun Han, Narelle Keating, Hailun Li, Geetha Rao, Jonathan Bohlen, Charles S. Lay, Simon Platt, Gaspard Kerner, Elsa Feredj, , Stéphanie Boisson‐Dupuis

Homozygosity for hypomorphic IL23R variants (G149R, G300V, R381Q) partly impairs IL-23-dependent IFN-γ production in patient cells; with L372F (effect inferred), they are enriched in tuberculosis, not MSMD or CMC patients.

The Journal of Experimental Medicine · Jul 9, 2026Peer-reviewedGenetics✦ In-depth digest

Co-targeting MERTK and EGFR with a Bispecific Antibody Overcomes Drug Resistance Across Mutations in Exons 19, 20, and 21

Suvendu Giri, Boobash-Raj Selvadurai, Arturo Simoni Nieves, Nitin Gupta, Moshit Lindzen, Rishita Chatterjee, Alessandro Genna, Marieke Van Daele, Deepthi Ramesh-Kumar, Mirie Zerbib, Roni Oren, Isabelle Sophie Meijer, Elisabeth Franziska Wippich, Yahel Avraham, Rony Dahan, , Yosef Yarden

This study develops a bispecific antibody targeting MERTK and EGFR to overcome drug resistance in lung cancer with mutations in exons 19, 20, and 21.

bioRxiv · Oct 16, 2025 · PreprintCancer Biology