Meng Michelle Xu

The paper introduces UCASpatial, an ultra-precision spatial transcriptomics deconvolution algorithm, to improve the identification of immune cell subpopulations and their functional roles in tissue microenvironments.

The paper identifies eQTLs, rQTLs, and pQTLs in the human brain and shows that many eQTL effects are attenuated post-transcriptionally, yet still correlate with schizophrenia GWAS signals.

This study identifies fever and infection as major agonal factors affecting gene expression in postmortem brains and recommends correcting for these factors using PEER or SVA.