Jonas Poehls

The paper identifies 1,400 stop codon readthrough genes in Drosophila, reveals sequence features associated with programmed readthrough, and shows conserved cis-elements functional in mammalian cells.

The paper analyzes amino acid misincorporation rates across 14 species, finding that codon and amino acid usage explain error rates, with 70% of errors due to codon-anticodon mispairing.

The paper identifies and characterizes ribosomal frameshifting sites across organisms, showing their prevalence and evolutionary tuning to mitigate harmful effects.

The paper quantifies stop codon miscoding in E. coli under stress, showing up to 80% error rates and environmental regulation of protein heterogeneity.