Author

Francesca Di Leva

University of TrentoORCID 0000-0002-6167-0679Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Emanuela KerschbameriD· 2 shared Erik DassiiD· 2 shared Marta BiagioliiD· 2 shared Silvano PiazzaiD· 2 shared Takshashila TripathiiD· 2 shared Alan MonzianiiD· 1 shared Christoph DieterichiD· 1 shared Dilara AyyildiziD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersGenetics

Emanuela KerschbamerORCID

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2 papers

Recent·Most cited

GeneticsNucleic Acids ResearchPeer-reviewedNov 10, 2022

CHD8 Suppression Impacts on Histone H3 Lysine 36 Trimethylation and Alters RNA Alternative Splicing.

Emanuela Kerschbamer, Michele Arnoldi, Takshashila Tripathi…·Marta Biagioli

This study shows that CHD8 suppression reduces H3K36me3 levels and alters alternative splicing of ~2000 genes, linking CHD8 to RNA processing and ASD.

27 citations

humanChIP-seq

𝕏 PostBluesky

GeneticsbioRxivPreprintDec 27, 2021

Defective linear and circular RNAs biogenesis in Huntington's disease: CAG repeat expansion hijacks neuronal splicing

Dilara Ayyildiz, Alan Monziani, Takshashila Tripathi…·Marta Biagioli

The paper shows that CAG repeat expansion in Huntington's disease disrupts splicing, reducing circular RNA production and affecting neural progenitors and striatum before symptoms appear.

2 citations

mousebulk RNA-seq

𝕏 PostBluesky