NeurosciencebioRxivPreprint
Bridging Stem Cell Models and Medicine: Integrated 3D Human Cerebral Organoids and Pediatric Serum Reveal Mechanisms and Biomarkers of Anesthetic-Induced Neurotoxicity
Tarun Pant, Congshan Jiang, Yasheng Yan…·Xiaowen Bai
This study uses 3D human cerebral organoids and pediatric serum to identify molecular signatures of anesthetic-induced neurotoxicity, revealing shared dysregulated RNAs linked to neuronal injury and neurodevelopmental disruption.
DOI 10.1101/2025.04.23.650256