Cancer BiologybioRxivPreprint
Integrative CRISPR Screens and RNA-Omics Discover an Essential Role for PUF60-3' Splice Site Interactions in Cancer Progression
Alexandra T. Tankka, Jaclyn M. Einstein, Catherine J. Zhou…·Gene Wei-Ming Yeo
The paper identifies PUF60's role in cancer progression by combining CRISPR screens and RNA-omics, showing its splicing activity supports TNBC proliferation and is a potential therapeutic target.
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