Alicia Roque

The paper investigates how N6-methyladenosine (m6A) regulates different histone H1 subtypes, identifying m6A readers and proposing a model for subtype-specific regulation.

This study evaluates the antimicrobial and antibiofilm activity of human recombinant H1 histones against Pseudomonas aeruginosa, showing efficacy and safety in vitro and in vivo.

The paper develops a mass spectrometry-based PRM assay to quantify histone H1 subtypes and shows differences in H1 complement between CML responders and non-responders.

The paper investigates the proteasome-dependent degradation of histone H1 subtypes, showing that their C-terminal domain mediates degradation by the 20S proteasome.

The paper investigates the regulation of histone H1 somatic subtypes using integrated OMICs data, finding that transcriptional control and co-regulation explain variability in H1 complement and subtype dynamics.