Author

Thenappan Thenappan

University of MinnesotaORCID 0000-0002-6210-0467Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 3 Assay:whole-exome sequencing· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Adaani FrostiD· 3 shared Erika B. RosenzweigiD· 3 shared Ferhaan AhmadiD· 3 shared Fernando TorresiD· 3 shared James Klinger· 3 shared Jean ElwingiD· 3 shared Katie A. LutziD· 3 shared Michael W. PauciuloiD· 3 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenetics

Adaani FrostORCID

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4 papers

Recent·Most cited

PhysiologyCirculation Heart FailurePeer-reviewedMay 16, 2025

Lactobacillus Restructures the Micro/Mycobiome to Combat Glycoprotein-130 Associated Microtubule Remodeling and Right Ventricular Dysfunction in Pulmonary Arterial Hypertension

Sasha Z. Prisco, Madelyn Blake, Felipe Kazmirczak…·Kurt W. Prins

This study shows Lactobacillus modulates the gut microbiome to reduce inflammation and improve RV function in PAH by counteracting GP130-mediated microtubule remodeling.

12 citationstop 2%

mousehuman

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GeneticsGenome MedicinePeer-reviewedMay 10, 2021

Rare variant analysis of 4,241 pulmonary arterial hypertension cases from an international consortium implicate FBLN2, PDGFD and rare de novo variants in PAH

Na Zhu, Emilia M. Swietlik, Carrie L. Welch…·National Cohort Study of Idiopathic and Heritable PAH

This study identifies two new PAH risk genes, FBLN2 and PDGFD, through rare variant analysis of 4,241 PAH cases, with de novo variants contributing to ~15% of pediatric IPAH.

84 citationstop 1%

humanwhole-exome sequencing

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GeneticsGenome MedicinePeer-reviewedNov 14, 2019

Novel risk genes and mechanisms implicated by exome sequencing of 2,572 individuals with pulmonary arterial hypertension

Na Zhu, Michael W. Pauciulo, Carrie L. Welch…·William C. Nichols

The paper identifies two new risk genes for idiopathic pulmonary arterial hypertension through exome sequencing of 2,572 individuals.

136 citationstop 1%

humanwhole-exome sequencing

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GeneticsThe Lancet Respiratory MedicinePeer-reviewedDec 5, 2018

Genetic determinants of risk and survival in pulmonary arterial hypertension

Christopher J. Rhodes, Ken Batai, Marta Bleda…·Quinten Waisfisz

This study identifies common genetic variants associated with pulmonary arterial hypertension risk and survival, focusing on HLA-DPA1/DPB1 and a SOX17 enhancer locus.

212 citations

humanGWAS summary statistics

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