Felipe Kazmirczak

This study uses multi-omics profiling to identify molecular mechanisms contributing to progressive right ventricular dysfunction in pigs.

This study shows Lactobacillus modulates the gut microbiome to reduce inflammation and improve RV function in PAH by counteracting GP130-mediated microtubule remodeling.

This study identifies ER-mitochondrial dysfunction and inflammatory macrophages as drivers of right atrial dysfunction using multi-omic analyses in a pulmonary artery banded swine model.

SC144 improves right ventricular function in pulmonary artery banded pigs by reducing inflammation, restoring metabolism, and enhancing cell communication.

This study shows ferroptosis inhibition improves cardiac function and metabolism in a large animal model of right heart failure.