PathologyMicroorganismsPeer-reviewed
Hepatitis E ORF2 blocks trophoblast autophagy to induce miscarriage via LC3B binding rather than PI3K/Akt/mTOR pathway suppression
Yinzhu Chen, Yifei Yang, Qianyu Bai…·Tianlong Liu
This study identifies that HEV ORF2 blocks trophoblast autophagy by binding LC3B, leading to miscarriage, independent of the PI3K/Akt/mTOR pathway.
DOI 10.3390/microorganisms14010181